Rina Eiden's research focuses on understanding developmental trajectories among children at risk for maladjustment due to multiple adversities linked to parental substance abuse, as well as early childhood interventions designed to ameliorate these risks and promote competence. Her studies, many of which follow cohorts of children across multiple developmental stages (e.g., birth to adolescence), seek to understand developmental mechanisms that may explain the association between parental risk factors and child outcomes (e.g., infant-parent attachment, parent-child self-regulation, individual differences in children’s autonomic and stress reactivity, and immune/inflammatory mechanisms). She has a particular interest in prenatal and early childhood interventions for substance using parents, with the goal of promoting family health, including positive developmental cascades for children.
Current projects include:
- a randomized clinical trial to promote co-parenting and reduce father hazardous drinking in expectant parents;
- a translational (human-animal) study of prenatal tobacco and cannabis exposure effects on middle childhood outcomes in a sample recruited in pregnancy;
- developmental pathways to violence, victimization, and substance use in a sample exposed to cocaine and other substances in utero;
- a collaborative study on the effects of prenatal cocaine on early brain functional connectivity and behavior; and
- collaborations on two randomized clinical trials: 1) to enhance alternatives to eating in infancy, and 2) to prevent postpartum smoking relapse by breastfeeding promotion.
Kong, K. L., Eiden, R. D., Morris, K. S., Paluch, R. A., Carr, K. A., & Epstein, L. H. (2022). Reducing relative food reinforcement of infants using a music enrichment program: a randomized, controlled trial. The American Journal of Clinical Nutrition. Advance online publication.
Zhao, J., Ettekal, I., Nickerson, A. B., Schuetze, P., Shisler, S., Godleski, S., Ostrov, J., & Eiden, R. D. (2022). Child community violence exposure in an at-risk sample: Developmental trajectories, caregiving risks, and the role of child temperament. Psychology of Violence. Advance online publication. https://doi.org/10.1037/vio0000416
Kong, K. L., Shisler, S., Eiden, R.D., Anzman-Frasca, S., & Piazza, J. (2022). Examining the relationship between infant weight status and parent–infant interactions within a food and nonfood context. Childhood Obesity. Advance online publication. https://doi.org/10.1089/chi.2021.0126
Miller, S.E., Maggs, J.L., Eiden, R.D. & Almeida, D.M. (2022). Familial predictors of alcohol and drug use-related problems among middle-aged and older adults. Journal of Family Issues. Advance online publication. https://doi.org/10.1177/0192513X211064877
Ettekal, I., Eiden, R. D., Schuetze, P., & Nickerson, A. (2019). Comparing alternative methods of measuring cumulative risk based on multiple risk indicators: Are there differential effects on children’s externalizing problems? PLOS One, 14, 7, e0219134. https://doi.org/10.1371/journal.pone.0219134
De Genna, N.M., Stroud, L.R., Eiden, R.D. (2019). Co-use of tobacco and marijuana during pregnancy: Impact on nervous system development. Neurotoxicology and Teratology, 74, 106807. https://doi.org/10.1016/j.ntt.2019.04.004
Wen X., Eiden R. D., Justicia-Linde F. E., Wang Y, Higgins S. T., Kong K. K., Shittu A, Perkins J. M., Esadah P, Mautner T, Epstein L. H. (2019). Reducing fetal origins of childhood obesity through maternal smoking cessation during pregnancy: an intervention study. International Journal of Obesity, 43,(7): 1435-1439. (PMID: 30518822)
Wen X, Eiden R. D., Justicia-Linde FE, Wang Y, Higgins ST, Thor N, Haghdel A, Peters AR, Epstein LH. (2019). A multicomponent behavioral intervention for smoking cessation during pregnancy: a non-concurrent multiple baseline design. Translational Behavioral Medicine, 9(2), 308-318. PMCID: PMC6610210.
Schuetze, P., Zhao, J., Eiden, R. D., Shisler, S., Huestis, M. A. (2019). Prenatal exposure to tobacco and marijuana and child autonomic regulation and reactivity: An analysis of indirect pathways via maternal psychopathology and parenting. Developmental Psychobiology, 61(7), 1022-1034. doi: 10.1002/dev.2184
Ettekal, I., Eiden, R. D., Nickerson, A. B., Molnar, D. S., & Schuetze, P. (2019). Developmental cascades to children’s conduct problems: The role of prenatal substance use, socioeconomic adversity, maternal depression and sensitivity, and children’s conscience. Development and Psychopathology, 32(1), 89-103, (Epub ahead of print). PMCID: PMC6675677.
Prenatal exposure to tobacco and cannabis: Effects on autonomic and emotion regulation
Eiden, R.D., Schuetze, P., Shisler, S., & Huestis, M.A. (2018). Prenatal exposure to tobacco and cannabis: Effects on autonomic and emotion regulation. Neurotoxicology and Teratology, 68, 47-56. PMCID: PMC6161361
Pre-and postnatal tobacco and cannabis exposure and child behavior problems: Bidirectional associations, joint effects, and sex differences
Eiden, R.D., Zhao, J., Casey, M., Schuetze, P., Shisler, S., Colder, C.R. (2018). Pre-and postnatal tobacco and cannabis exposure and child behavior problems: Bidirectional associations, joint effects, and sex differences. Drug and Alcohol Dependence, 185, 82-92. PMCID: PMC5889743
October 18, 2021
Penn State receives grant to study factors promoting early childhood development
The effects of genetics, home environment, and prenatal substance use on child health and brain development are largely unknown, even though pregnancy and early childhood are incredibly important periods of growth. To address this knowledge gap, Penn State was recently awarded a five-year, $5.8 million grant and selected as part of a longitudinal NIH-funded consortium called the HEALthy Brain and Child Development (HBCD) Study.Read more.
June 11, 2021
Training scientists in substance use prevention the focus of $3.2 million grant
A $3.2 million grant from the National Institute on Drug Abuse (NIDA) will fund the continuation of Penn State's Prevention and Methodology Training (PAMT) program, which focuses on training the next generation of scientists in preventing substance use and addiction.Read more.